EEG - fMRI

Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are very important and complementary modalities since fMRI offers high spatial resolution while EEG provides a direct measurement of neuronal activity with high temporal resolution. Interest in the integration of these two types of data is growing rapidly as it promises to yield important new insights into human brain activity, as has already occurred in the case of epilepsy. Indeed, it seems certain that integrated EEG-fMRI will play an increasing role in neuroscience and in the clinical study of various brain disorders. This book discusses in depth all aspects of EEG-fMRI, including physiological principles and technical and methodological issues such as EEG artefact reduction methods, image quality, and data analysis strategies. Detailed consideration is given to all potential applications, primarily in the fields of sleep research, cognitive neuroscience, and clinical neurology and psychiatry. All of the authors are recognized experts in the field, and the text is supported by numerous informative illustrations.

Table of contents

General Physiology: The BOLD fMRI contrast mechansim.- Physiological Basis of the EEG.- Neurophysiological investigation of the basis of the fMNRI signal.- Fundamental Questions Concerning the Combination of EEG and fMRI:Simultaneous versus separate measurement of EEG and fMRI.- Comparison between EEG-based results and fMRI.- Acquisition and Preprocessing of Simultaneous EEG and fMRI: Feasibility and safety of simultaneous EEG/fMRI measurements.- Correction of gradient artefacts.- Corrections of cardioballistic artefacts.- Statistical Procedures and Models: Single trial coupling of EEG and fMRI.- Hemodynamic correlates of EEG: a heuristic.- Applications: The BOLD-response and frequency bands.-Vigilance.- Sleep research.- Investigation of the auditory system.- Investigation of the visual system.- Pain.- Epilepsy.- Applications in psychiatry.- Investigation of Cognitive Functions.- Simultaneous measurement of EEG and fMRI in the monkey.- Simultaneous EEG and fMRI at high fields.- High frequency oscillations and fMRI.