Marijuana and Madness 2/e

The second edition of this critically acclaimed and award-winning text provides a comprehensive overview of the psychiatry and neuroscience of Cannabis sativa (marijuana). It outlines the very latest developments in our understanding of the human cannabinoid system, and links this knowledge to clinical and epidemiological facts about the impact of cannabis on mental health. Clinically focused chapters review not only the direct psychomimetic properties of cannabis, but also the impact consumption has on the courses of evolving or established mental illnesses such as schizophrenia. Effects of cannabis on mood are reviewed, as are its effects on cognition. This new edition has been extensively updated and expanded with 10 new chapters to incorporate major new research findings. This book will be of interest to all members of the mental health team, as well as to neuroscientists, epidemiologists, public health specialists and those involved in drug and alcohol research.

Features

• Winner of the Mental Health Book of the Year award for 2005 from the British Medical Association
• Covers basic science, epidemiology and clinical aspects, presenting a multidimensional approach
• Written by international leading researchers and clinicians

Table of Contents

Foreword
Preface
Part I. Pharmacology of Cannabis and the Endocannabinoid System: 1. The cannabinoid system from the point of view of a chemist Raphael Mechoulam and Lumir Hanus
2. The function of the endocannabinoid system Roger Pertwee
3. How cannabis works in the brain Leslie Iversen
Part II. The Changing Face of Cannabis: 4. The epidemiology of cannabis use: an international perspective Sandeep Chawla
5. Is cannabis becoming more potent? Mahmoud ElSohly and David Potter
6. Health policy and cannabis Wayne Hall and Louisa Degenhardt
Part III. Cannabis and the Brain: 7. Cannabis, endocannabinoids and neurodevelopment Ismael Galve-Roperh
8. The impact of pubertal exposure to cannabis on the brain: a focus on animal studies Miriam Schneider
9. Cannabis and cognition: short and long-term effects Nadia Solowij
10. Does cannabis cause lasting brain damage? Nadia Solowij, Murat Yucel, Valentina Lorenzetti and Dan Lubman
Part IV. Cannabis, Anxiety and Mood: 11. Acute and subacute psychiatric effects of cannabis David Castle and Nadia Solowij
12. The association between cannabis use and depression Louisa Degenhardt, Wayne Hall, Michael Lynskey, Carolyn Coffey and George Patton
13. Cannabis and bipolar disorder Carol Silberberg and David Castle
Part V. Cannabis and Psychosis: 14. Cannabis and psychosis proneness Jim van Os, Helene Verdoux and David Castle
15. Genetic factors that moderate the psychomimetic effects of cannabis Marta Di Forti, Robin M. Murray and Cecile Henquet
16. Cannabis causes positive, negative, cognitive symptoms and produces impairments in electrophysiological indices of information processing Mohini Ranganathan, Andrew Sewell, Daniel Mathalon and D. Cyril D'Souza
17. The neural basis for the acute effects of cannabis on learning and psychosis Sagnik Bhattacharrya and Phil McGuire
Part VI. Cannabinoids and Schizophrenia: Aetiopathology and Treatment Implications: 18. Does cannabis cause schizophrenia? Stan Zammit, Mary Cannon and Robin M. Murray
19. Postmortem studies of the brain cannabinoid system in schizophrenia Suresh Sundram, Brian Dean and David Copolov
20. The endogenous cannabinoid system in schizophrenia Paul Morrison
21. The endocannabinoid system as a target for pharmacotherapy of schizophrenia Markus Leweke
Part VII. Cannabis and its Impact on Schizophrenia: 22. Acute effects of cannabis in established schizophrenia Cecile Henquet and D. Cyril D'Souza
23. Cannabis and the long-term course of schizophrenia Don Liszen, Bart Peters and Lieuwe De Haan
24. Motives that maintain cannabis use in schizophrenia Kim Meuser
25. Treatment interventions for cannabis abuse in people with psychosis Wynne James and David Castle
Part VIII. Integration: 26. Cannabis and mental illness: an integration D. Cyril D'Souza, Robin M. Murray and David Castle
Index.