Myology

The most comprehensive reference on neuromuscular diseases and disorders! - Edited by the world's leading authority, this is the reference of choice for neurologists who a need a complete, authoritative work on muscle diseases and disorders. Features over 100 color illustrations of clinical, pathological, and imaging studies in myology. Includes important information on muscular dystrophy and inflammatory disease as well as a better understanding of mitochondrial diseases and the genetic basis of inherited diseases.

Contents
SCIENTIFIC BASIS - Development, Differentiation and Diversity - 1 The Embryonic Origin of Muscle - 2 Morphogenesis of skeletal muscle fibers - 3 Satellite and stem cells; muscle regeneration - 4 The Diversity of Muscle Fibers and its Origin - 5 Physiology of Motor Units and their Control - 6 The extraocular muscles, Muscle contraction - 7 The Structure of Contractile Filaments - 8 The Structure of Vertebrate Muscle Myosin - 9 The Cross Bridge Cycle and the Energetics of Muscle Contraction - The control of muscle fiber activity - 10 Ionic Channels and their Function in Muscle Activity - 11 The Sarcoplasmic Reticulum and the Transverse Tubules - 12 Excitation-Contraction Coupling in Skeletal Muscle - 13 Activation of the Contractile Mechanism by Calcium - 14 The Proteins of the Sarcoplasmic Reticulum - Neuromuscular transmission - 15 The Neuromuscular Junction - 16 Neuromuscular Transmission - 17 Acetylcholine receptors: Structure function - 18 Function and Molecular Structure of Acetylcholinesterase - Muscle as a tissue - 19 The Subcortical Cytoskeleton and the Plasma Membrane - 20 The Extracellular Matrix - 21 The Muscle Spindle - 22 The Microcirculation of Muscle - 23 Protein and Amino Acid Metabolism in Muscle - 24 Lysosomal Metabolism and its Relevance to Skeletal Muscle - GENERAL APPROACHES TO NEUROMUSCULAR DISEASES - 25 The clinical examination - 26 Electrodiagnosis of Muscle disorders - 27 Muscle Imaging - 28 Noninvasive evaluation of metabolic myopathies - 29 The Muscle Biopsy - 30 Basic Reactions of Muscle - 31 Ultrastructural changes in diseased muscle - 32 Immune Mechanisms in Muscle Diseases - 33 The Tools of Molecular Genetics And Their Application to the Study Of Muscle Diseases - DISEASES OF MUSCLE - Muscular Dystrophies - 34 Dystrophinopathies - 35 Emery-Dreifuss Muscular Dystrophy - 36 Myotonic Dystrophy - 37 Limb Girdle Dystrophies - 38 Facioscapulohumeral Dystrophy and Scapuloperoneal Syndrome - 39 Bethlem Myopathy - 40 Oculopharyngeal Muscular Dystrophy - 41 X-Linked Vacuolar Myopathy - 42 Distal Muscular Dystrophies - 43 Myofibrillar Myopathies - 44 Congenital Muscular Dystrophies - 45 Cardiomyopathies Associated with Muscular Dystrophies - Altered Excitability of the Cell Membrane - 46 Nondystrophic Channelopathies: Myotonias and Per Paralyses - 47 Neuromyotonia - Inflammatory Myopathies - 48 Polymyositis and Dermatomyositis Syndromes - 49 Sporadic Inclusion Body Myositis - 50 Inclusion Body Myopathy - 51 Virus Related Muscle Diseases - 52 Parasitic Myositis - 53 Other Inflammatory Myopathies - Congenital Myopathies 54 Congenital Myopathies - Metabolic Disorders Affecting Muscle - 55 Nonlysosomal Glycogenoses (and review of carbohydrate metabolism) - 56 Acid Maltase Deficiency - 57 Disorders of Lipid Metabolism (and review of lipid metabolism) - 58 Mitochondrial Diseases - 59 Malignant Hyperthermia - 60 Myoglobinura - 61 Myopathies due to Drugs, Toxins, and Nutritional Deficiency - 62 Endocrine Myopathies - 63 Muscle Pain, Cramps, and Fatigue - Disturbances of Neuromuscular Transmission - 64 Autoimmune Myasthenia Gravis - 65 Lambert-Eaton Myasthenic Syndrome - 66 Congenital Myasthenic Syndromes - Neural Diseases - 67 Motor Neuron Diseases in Children - 68 Motor Neuron Diseases in Adults - 69 Disease of Peripheral Nerves - 70 Congenital Deformities